LAMR1CT (AA 201-295) antibody

Catalog No. ABIN729598

This Rabbit Polyclonal antibody specifically detects LAMR1CT in ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p) and WB. It exhibits reactivity toward Human, Mouse and Rat. It has been mentioned in 2+ publications

Quick Overview for LAMR1CT (AA 201-295) antibody (ABIN729598)

Target: LAMR1CT

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Product Details

Binding Specificity: AA 201-295

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LAMR1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References

Liu, Sun, Wu, Shi, Wang, Wang, Zhang, Zhang, Zhang: "MGr1-Ag/37LRP promotes growth and proliferation of gastric cancer in vitro and in vivo." in: Cancer gene therapy, Vol. 21, Issue 9, pp. 355-63, (2014) (PubMed).

Zhang, Wang, Xu, Dong, Liu, Zhou, Pang, Ma, Zhang, Pei, Zhang, Liu: "MGr1-Ag promotes invasion and bone metastasis of small-cell lung cancer in vitro and in vivo." in: Oncology reports, Vol. 29, Issue 6, pp. 2283-90, (2013) (PubMed).

Target Details

Target: LAMR1CT

Background:

Synonyms: SA, LBP, LRP, p4, 67LR, ICAS, lamR, 37LRP, LAMBR, LAMR1, LRP/LR, LBP/p4, NEM/1CHD4, 4S ribosomal protein SA, 37 kDa laminin receptor precursor, 37/67 kDa laminin receptor, 67 kDa laminin receptor, Colon carcinoma laminin-binding protein, Laminin receptor 1, Laminin-binding protein precursor p4, Multidrug resistance-associated protein MGr1-Ag, RPSA

Background: Required for the assembly and/or stability of the 4S ribosomal subunit. Required for the processing of the 2S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 4S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Acts as a PPP1R16B-dependent substrate of PPP1CA. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria.

Gene ID: 3921

UniProt: P08865