CBX5 antibody (pTyr37) (HRP)

Catalog No. ABIN730297

This Rabbit Polyclonal antibody specifically detects CBX5 in ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for CBX5 antibody (pTyr37) (HRP) (ABIN730297)

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX5 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CBX5 Antibody (HRP)

Binding Specificity: pTyr37

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human CBX5 around the phosphorylation site of Tyr37

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CBX5

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Alternative Name: CBX5

Background:

Synonyms: Antigen p25, Cbx 5, Cbx5, CBX5_HUMAN, CG8409, Chromobox homolog 5 Drosophila HP1 alpha, Chromobox homolog 5 HP1 alpha homolog Drosophila, Chromobox homolog 5 HP1 alpha homolog, Drosophila, chromobox homolog 5, HP1 alpha homolog, Chromobox protein homolog 5, Chromobox protein homologue 5, Heterochromatin protein 1 alpha, Heterochromatin protein 1, Heterochromatin protein 1, HP 1, HP 1A, HP1 alpha homolog, HP1, HP1A, HP1Hs alpha, Suvar205, HP1a, HP1Hs-alpha, HP1 alpha, Antigen p25, Heterochromatin protein 1 homolog alpha.

Background: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq].

Gene ID: 23468