ALDH1A1 antibody (AA 315-434) (CF®488A)

Catalog No. ABIN7649329

This Mouse Monoclonal antibody specifically detects ALDH1A1 in . It exhibits reactivity toward Human.

Quick Overview for ALDH1A1 antibody (AA 315-434) (CF®488A) (ABIN7649329)

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ALDH1A1 antibody is conjugated to CF®488A

Application: Please inquire

Clone: ALDH1A1-1382

Product Details anti-ALDH1A1 Antibody (CF®488A)

Binding Specificity: AA 315-434

Purpose: ALDH1A1 (Aldehyde Dehydrogenase 1A1)(ALDH1A1/1382), CF488A conjugate

Characteristics: Aldehyde dehydrogenase 1 family member A1 (ALDH1A1), also known as retinal dehydrogenase 1, belongs to the aldehyde dehydrogenase enzyme family, which is involved in the metabolism of alcohol. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Purified recombinant fragment of human ALDH1A1 (aa 315-434), expressed in HK293 Cells.

Isotype: IgG

Application Details

Application Notes: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Comment:

Positive Control: HepG2 or A549 cells. Colon or Testicular Carcinoma.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for ALDH1A1

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Alternative Name: Aldehyde dehydrogenase 1

Background:

Synonyms: Aldehyde dehydrogenase family 1 member A1, ALDH1A1, Retinal dehydrogenase 1, Retinaldehyde Dehydrogenase 1, Epididymis Luminal Protein

Gene Symbol: ALDH1A1

Molecular Weight: 56 kDa

Gene ID: 216

UniProt: P00352

Pathways: Dopaminergic Neurogenesis