BARX1 antibody (Biotin)

Catalog No. ABIN7649995

This Mouse Monoclonal antibody specifically detects BARX1 in IHC and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for BARX1 antibody (Biotin) (ABIN7649995)

Target: BARX1 (BARX Homeobox 1 (BARX1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BARX1 antibody is conjugated to Biotin

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: BARX1-2760

Product Details anti-BARX1 Antibody (Biotin)

Purpose: BARX1 (Prognostic Biomarker in Hepatocellular Carcinoma)(BARX1/2760), Biotin conjugate

Characteristics: BarX1 is a member of the Bar subclass of homeobox transcription factors. Studies of the Mouse and chick homolog suggest the encoded protein may play a role in developing teeth and craniofacial mesenchyme of neural crest origin. The protein may also be associated with differentiation of stomach epithelia. Down-regulation of Barx1 promotes hepatocellular carcinoma cell (HCC) migration, invasion and metastasis, whereas up-regulation of Barx1 inhibits HCC migration, invasion and metastasis. The loss of Barx1 expression represents a prognostic biomarker in human HCC. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human BARX1 protein.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: HepG2 cell lysate. Human pancreas.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for BARX1

Target: BARX1 (BARX Homeobox 1 (BARX1))

Alternative Name: BARX1

Background:

Synonyms: BARX1, Homeobox protein BarH-like 1, BARX homeobox 1

Gene Symbol: BARX1

Molecular Weight: 24 kDa

Gene ID: 56033

Pathways: Sensory Perception of Sound