CALB1 antibody (AA 7-96) (CF®405S)

Catalog No. ABIN7650277

This Mouse Monoclonal antibody specifically detects CALB1 in . It exhibits reactivity toward Human.

Quick Overview for CALB1 antibody (AA 7-96) (CF®405S) (ABIN7650277)

Target: CALB1 (Calbindin (CALB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CALB1 antibody is conjugated to CF®405S

Application: Please inquire

Clone: CALB1-2364

Product Details anti-CALB1 Antibody (CF®405S)

Binding Specificity: AA 7-96

Purpose: Calbindin 1 (CALB1)(CALB1/2364), CF405S conjugate

Characteristics: Calbindin 1, also known as calbindin D28K, is a member of a family of calcium binding proteins. This protein family also includes calmodulin, calbindin 2, S-100, and troponin C. Calbindin 1 is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, calbindin 1 acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, calbindin 1 modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, calbindin 1 has been implicated to play a role in apoptosis and microtubule function. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment (around aa 7-96) of human CALB1 protein

Isotype: IgG1, kappa

Application Details

Application Notes: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Comment:

Positive Control: 293T or HepG2 cells. Prostate, Lung, Pancreas, Kidney and Liver.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for CALB1

Target: CALB1 (Calbindin (CALB1))

Alternative Name: Calbindin 1

Background:

Synonyms: Calbindin, Calbindin 1, Calbindin D28, Calbindin D28K, CALB1, Vitamin D dependent calcium binding protein

Gene Symbol: CALB1

Molecular Weight: 52 kDa

Gene ID: 793

UniProt: P05937