CALB1 antibody (AA 7-96)

Catalog No. ABIN7650305

The Mouse Monoclonal anti-CALB1 antibody has been validated for IHC and IHC (fp). It is suitable to detect CALB1 in samples from Human.

Quick Overview for CALB1 antibody (AA 7-96) (ABIN7650305)

Target: CALB1 (Calbindin (CALB1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CALB1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: CALB1-2782

Product Details anti-CALB1 Antibody

Binding Specificity: AA 7-96

Purpose: Calbindin 1 (CALB1)(CALB1/2782)

Characteristics: Calbindin 1, also known as calbindin D28K, is a member of a family of calcium binding proteins. This protein family also includes calmodulin, calbindin 2, S-100, and troponin C. Calbindin 1 is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, calbindin 1 acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, calbindin 1 modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, calbindin 1 has been implicated to play a role in apoptosis and microtubule function. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment (around aa 7-96) of human CALB1 protein

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: 293T or HepG2 cells. Prostate, Lung, Pancreas, Kidney and Liver.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, no BSA, no azide

Preservative: Without preservative

Storage: -20 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Store at -20 °C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for CALB1

Target: CALB1 (Calbindin (CALB1))

Alternative Name: Calbindin 1

Background:

Synonyms: Calbindin, Calbindin 1, Calbindin D28, Calbindin D28K, CALB1, Vitamin D dependent calcium binding protein

Gene Symbol: CALB1

Molecular Weight: 52 kDa

Gene ID: 793

UniProt: P05937