Recombinant CD79b antibody (AA 29-159) (CF®740)

Catalog No. ABIN7651995

This anti-CD79b antibody is a Rabbit Monoclonal antibody detecting CD79b in . Suitable for Human.

Quick Overview for Recombinant CD79b antibody (AA 29-159) (CF®740) (ABIN7651995)

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD79b antibody is conjugated to CF®740

Application: Please inquire

Clone: IGB-2940R

Product Details anti-CD79b Antibody (CF®740)

Binding Specificity: AA 29-159

Purpose: CD79b (B-Cell Marker)(IGB/2940R), CF740 conjugate

Characteristics: CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human CD79b protein fragment (around aa29-159)

Isotype: IgG

Application Details

Application Notes: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Comment:

Positive Control: Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for CD79b

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79b

Background:

Synonyms: AGM6, B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, B29, B29/Ig-beta/CD79b, CD79b, Ig-beta, IGB, Immunoglobulin-associated B29 protein

Gene Symbol: CD79B

Tissue Expression: NK cells|T-cells

Molecular Weight: 39 kDa

Gene ID: 974

UniProt: P40259

Pathways: BCR Signaling