F13A1 antibody (AA 46-181) (CF®740)

Catalog No. ABIN7652469

This anti-F13A1 antibody is a Mouse Monoclonal antibody detecting F13A1 in . Suitable for Human.

Quick Overview for F13A1 antibody (AA 46-181) (CF®740) (ABIN7652469)

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This F13A1 antibody is conjugated to CF®740

Application: Please inquire

Clone: F13A1-1447

Product Details anti-F13A1 Antibody (CF®740)

Binding Specificity: AA 46-181

Purpose: Factor XIIIa (Coagulation Factor XIIIA Chain) (F13A1/1447), CF740 conjugate

Characteristics: This antibody recognizes a protein of 83 kDa, which is identified as Factor XIIIa. It has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/ ) and desmoplastic malignant melanoma (-). Anti-factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment of human Factor XIIIa protein (aa46-181)

Isotype: IgG2a

Application Details

Application Notes: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Comment:

Positive Control: 293T Cells. Placenta.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for F13A1

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Alternative Name: Factor-XIIIa

Background:

Synonyms: Coagulation factor XIII A chain, Coagulation factor XIII A1 polypeptide, Coagulation factor XIIIa, F13A, F13a1, Factor XIIIA, Fibrin stabilizing factor, A subunit, Fibrinoligase, FSF, A subunit, Protein-glutamine gamma-glutamyltransferase A chain, TGase, Transglutaminase A chain, Transglutaminase. plasma

Gene Symbol: F13A1

Tissue Expression: Platelets|Uterus|Megakaryocytes|Monocytes/macrophages|Placenta|Prostate

Molecular Weight: 83 kDa

Gene ID: 2162

UniProt: P00488