AARS2 antibody (AA 451-550) (HRP)

Catalog No. ABIN731927

The Rabbit Polyclonal anti-AARS2 antibody has been validated for ELISA, IHC (p) and IHC (fro). It is suitable to detect AARS2 in samples from Human, Mouse and Rat.

Quick Overview for AARS2 antibody (AA 451-550) (HRP) (ABIN731927)

Target: AARS2 (Alanyl-tRNA Synthetase 2, Mitochondrial (AARS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AARS2 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-AARS2 Antibody (HRP)

Binding Specificity: AA 451-550

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AARS2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for AARS2

Target: AARS2 (Alanyl-tRNA Synthetase 2, Mitochondrial (AARS2))

Alternative Name: AARS2

Background:

Synonyms: alanyl tRNA synthetase 2, AARSL, bA444E17.1, Gm89, MT ALARS, MTALARS , AARS 2, AARS2, Alanine tRNA ligase 2 mitochondrial, Alanine tRNA ligase, Alanyl tRNA synthetase 2 mitochondrial, Alanyl tRNA synthetase like, AlaRS, KIAA1270, MGC69820, Probable alanyl tRNA synthetase mitochondrial, RP11-444E17.1.

Background: The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. [provided by RefSeq, Dec 2011].

Gene ID: 57505