Cyclin D2 antibody (CF®640R)

Catalog No. ABIN7652776

This Mouse Monoclonal antibody specifically detects Cyclin D2 in . It exhibits reactivity toward Human.

Quick Overview for Cyclin D2 antibody (CF®640R) (ABIN7652776)

Target: Cyclin D2 (CCND2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cyclin D2 antibody is conjugated to CF®640R

Application: Please inquire

Clone: CCND2-2620

Product Details anti-Cyclin D2 Antibody (CF®640R)

Purpose: Cyclin D2(CCND2/2620), CF640R conjugate

Characteristics: Cyclins are a family of proteins that control how cells proceed through the multi-step cycle of cell division. Cyclin D2 helps to regulate a step in the cycle called the G1-S transition, in which the cell moves from the G1 phase, when cell growth occurs, to the S phase, when the cell's DNA is copied (replicated) in preparation for cell division. Cyclin D2's role in the cell division cycle makes it a key controller of the rate of cell growth and division (proliferation) in the body. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human Cyclin D2 (CCND2) protein

Isotype: IgG, kappa

Application Details

Application Notes: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Comment:

Positive Control: Cervical carcinoma. Esophagus.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for Cyclin D2

Target: Cyclin D2 (CCND2)

Alternative Name: Cyclin D2

Background:

Synonyms: CCND 2, ccnd2, CCND2_HUMAN, CyclinD2, G1/S specific cyclin D2, G1/S-specific cyclin-D2, KIAK0002, MGC102758, MPPH3

Gene Symbol: CCND2

Molecular Weight: 34 kDa

Gene ID: 894

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases