FABP2 antibody (CF®740)

Catalog No. ABIN7653931

This Mouse Monoclonal antibody specifically detects FABP2 in . It exhibits reactivity toward Human.

Quick Overview for FABP2 antibody (CF®740) (ABIN7653931)

Target: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FABP2 antibody is conjugated to CF®740

Application: Please inquire

Clone: CPTC-FABP2-3

Product Details anti-FABP2 Antibody (CF®740)

Purpose: FABP2 (Marker of Metastatic Potential in Colorectal Cancer)(CPTC-FABP2-3), CF740 conjugate

Characteristics: The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full length human FABP2 protein

Isotype: IgG1, kappa

Application Details

Application Notes: For coating for ELISA, order Ab without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution and staining procedure for a specific application should be determined by user. Recommended starting concentrations for titration are 1-2 μg/mL for most applications, or 1 μg/million cells/100 μLfor flow cytometry

Comment:

Positive Control: MOLT-4 and HEK-293 cell lines. Esophagus, Skin. Keratinocytes, highly expressed in psoriatic skin. Colon.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for FABP2

Target: FABP2 (Fatty Acid Binding Protein 2, Intestinal (FABP2))

Alternative Name: FABP2

Background:

Synonyms: FABPI, I-FABP, MGC133132, Fatty Acid-Binding Protein, Intestinal

Gene Symbol: FABP2

Molecular Weight: 15.21 kDa

Gene ID: 2169

UniProt: P12104