GATA3 antibody (AA 357-436) (CF®647)

Catalog No. ABIN7654311

This anti-GATA3 antibody is a Mouse Monoclonal antibody detecting GATA3 in IHC and IHC (fp). Suitable for Human.

Quick Overview for GATA3 antibody (AA 357-436) (CF®647) (ABIN7654311)

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GATA3 antibody is conjugated to CF®647

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: GATA3-2444

Product Details anti-GATA3 Antibody (CF®647)

Binding Specificity: AA 357-436

Purpose: GATA-3 (Breast and Urothelial Marker)(GATA3/2444), CF647 conjugate

Characteristics: GATA-3 is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. GATA-3 expression is primarily seen in breast and urothelial carcinomas. 'Therefore, GATA3 antibody can be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment of human GATA3 protein (around aa 357-436)

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: MCF-7 or T47D cells. Breast or Bladder Carcinoma.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for GATA3

Target: GATA3 (GATA Binding Protein 3 (GATA3))

Alternative Name: GATA-3

Background:

Synonyms: GATA3, GATA binding protein-3, GATA-binding factor 3, GATA3, HDR, HDRS, Transacting T-cell-specific transcription factor GATA-3

Gene Symbol: GATA3

Molecular Weight: ~50 kDa

Gene ID: 2625

UniProt: P23771

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation