GPX4 antibody (CF®740)

Catalog No. ABIN7654462

This Mouse Monoclonal antibody specifically detects GPX4 in IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GPX4 antibody (CF®740) (ABIN7654462)

Target: GPX4 (Glutathione Peroxidase 4 (GPX4))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This GPX4 antibody is conjugated to CF®740

Application: Immunofluorescence (IF)

Clone: LHM 2

Product Details anti-GPX4 Antibody (CF®740)

Purpose: GPX4 / MCSP(LHM 2), CF740 conjugate

Characteristics: The antioxidant enzyme glutathione peroxidase 4 (GPx4) catalyzes the reduction of peroxides through oxidation of cellular glutathione.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: A 375P cells crude extract

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: MCF7 or HepG2 cells. Human brain or malignant melanoma.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for GPX4

Target: GPX4 (Glutathione Peroxidase 4 (GPX4))

Alternative Name: GPX4

Background:

Synonyms: Glutathione Peroxidase 4 (GPX4), Melanoma-associated Chondroitin Sulfate Proteoglycan (MCSP), Phospholipid hydroperoxidase (PHGPx), Sperm nucleus glutathione peroxidase (snGPx)

Gene Symbol: GPX4

Molecular Weight: 21 kDa

Gene ID: 2879

UniProt: P36969