GLO1 antibody (CF®647)

Catalog No. ABIN7654589

The Mouse Monoclonal anti-GLO1 antibody has been validated for WB, IHC and IHC (fp). It is suitable to detect GLO1 in samples from Human.

Quick Overview for GLO1 antibody (CF®647) (ABIN7654589)

Target: GLO1 (Glyoxalase I (GLO1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GLO1 antibody is conjugated to CF®647

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: CPTC-GLO1-1

Product Details anti-GLO1 Antibody (CF®647)

Purpose: Lactoylglutathione Lyase(CPTC-GLO1-1), CF647 conjugate

Characteristics: GLO1 is an enzyme involved in the detoxification of methylgyoxal, a byproduct of glycolysis. GLO1 expression has been demonstrated by several studies to be upregulated in various human malignant tumors, including metastatic melanoma and lung carcinoma, and thus is a target for pharmaceutical development. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human full-length GLO1 protein

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: A431, HepG2, MOLT and Raji cell lysates. Ovarian carcinoma or prostate carcinoma.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for GLO1

Target: GLO1 (Glyoxalase I (GLO1))

Alternative Name: Lactoylglutathione Lyase

Background:

Synonyms: Aldoketomutase, epididymis secretory protein Li 74, Glo1, Glx I, glyoxalase 1 complex, glyoxalase 1 regulatory, glyoxalase 1 structural, glyoxalase domain containing 1, Glyoxalase I, glyoxylase 1, Ketone-aldehyde mutase, lactoyl glutathione lyase, Lactoylglutathione lyase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase

Gene Symbol: GLO1

Molecular Weight: 24-26 kDa

Gene ID: 2739

UniProt: Q04760