KRT15 antibody (CF®594)

Catalog No. ABIN7655961

This anti-KRT15 antibody is a Mouse Monoclonal antibody detecting KRT15 in IHC, FACS and IHC (fp). Suitable for Human.

Quick Overview for KRT15 antibody (CF®594) (ABIN7655961)

Target: KRT15 (Keratin 15 (KRT15))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT15 antibody is conjugated to CF®594

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: KRT15-2554

Product Details anti-KRT15 Antibody (CF®594)

Purpose: Cytokeratin 15 (Esophageal Squamous Cell Carcinoma Marker)(KRT15/2554), CF594 conjugate

Characteristics: Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human KRT15 protein

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: HeLa, A431 cells. Skin, Colon or Prostate.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for KRT15

Target: KRT15 (Keratin 15 (KRT15))

Alternative Name: Keratin 15

Background:

Synonyms: CK15, Cytokeratin 15, K1CO, Ka15, Keratin 15 basic, Keratin 15 beta, Keratin complex 1 acidic gene 15, Keratin type I cytoskeletal 15, KRT15, KRTB, KRTL15, Type I cytoskeletal 15, Type I keratin Ka15

Gene Symbol: KRT15

Tissue Expression: Epidermal cells

Molecular Weight: 52 kDa

Gene ID: 3866

UniProt: P19012