KRT4 antibody (AA 181-292)

Catalog No. ABIN7656185

The Mouse Monoclonal anti-KRT4 antibody has been validated for IHC, FACS, IF and IHC (fp). It is suitable to detect KRT4 in samples from Human.

Quick Overview for KRT4 antibody (AA 181-292) (ABIN7656185)

Target: KRT4 (Keratin 4 (KRT4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: KRT4-2804

Product Details anti-KRT4 Antibody

Binding Specificity: AA 181-292

Purpose: Cytokeratin 4 (KRT4)(KRT4/2804)

Characteristics: Cytokeratin 4 (KRT4) is an intermediate filament protein associated with Cytokeratin 13 (KRT13). It is expressed in suprabasal cells of non-keratinized stratified squamous epithelium of esophagus, cornea, anus, larynx, pharynx and tongue. Decreased expression of KRT4 is associated with head and neck squamous carcinoma. It is helpful in differentiation of squamous cell carcinoma of esophagus origin from that of thyroid origin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant fragment (around aa 181-292) of human KRT4 protein

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: HeLa, A549 or A431 cells. Skin, Cervix or Esophagus.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for KRT4

Target: KRT4 (Keratin 4 (KRT4))

Alternative Name: Keratin 4

Background:

Synonyms: CK4, CYK4, Cytokeratin 4, Keratin 4, Keratin type II cytoskeletal 4, KRT4

Gene Symbol: KRT4

Tissue Expression: Epithelial cells|Eye

Molecular Weight: 67 kDa

Gene ID: 3851

UniProt: P19013