MUC5AC antibody (CF®640R)

Catalog No. ABIN7657420

This Mouse Monoclonal antibody specifically detects MUC5AC in WB, IHC, RIA and IHC (fp). It exhibits reactivity toward Human, Mouse, Rat, Monkey, Cat, Rabbit, Chicken and Cow.

Quick Overview for MUC5AC antibody (CF®640R) (ABIN7657420)

Target: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Reactivity: Human, Mouse, Rat, Monkey, Cat, Rabbit, Chicken, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC5AC antibody is conjugated to CF®640R

Application: Western Blotting (WB), Immunohistochemistry (IHC), Radioimmunoassay (RIA), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: 1-13M1

Product Details anti-MUC5AC Antibody (CF®640R)

Purpose: MUC5AC (Mucin 5AC / Gastric Mucin)(1-13M1), CF640R conjugate

Characteristics: This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

Immunogen: M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient

Isotype: IgG1, kappa

Application Details

Application Notes: Does not react with Pig or Hedgehog. ELISA: For coating, purchase antibody without BSA. Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Optimal dilution for a specific application should be determined by user

Comment:

Positive Control: Human colon or stomach (IHC).

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for MUC5AC

Target: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Alternative Name: MUC5AC

Background:

Synonyms: Apomucin Major Airway Glycoprotein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin (TBM)

Gene Symbol: MUC5AC

Tissue Expression: Epithelial cells

Molecular Weight: >1,000 kDa

Gene ID: 4586

UniProt: P98088