Myoglobin antibody (CF®640R)

Catalog No. ABIN7657650

This anti-Myoglobin antibody is a Mouse Monoclonal antibody detecting Myoglobin in IHC and IHC (fp). Suitable for Human, Rat and Mouse.

Quick Overview for Myoglobin antibody (CF®640R) (ABIN7657650)

Target: Myoglobin (MB)

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Myoglobin antibody is conjugated to CF®640R

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: MB-2105

Product Details anti-Myoglobin Antibody (CF®640R)

Purpose: Myoglobin (Muscle Cell Marker)(MB/2105), CF640R conjugate

Characteristics: Myoglobin is a cytosolic oxygen-binding protein responsible for the storage and diffusion of oxygen within myocytes. Expression of myoglobin is highest in skeletal and cardiac muscle. Myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia. In combination with other striated muscle markers such as vimentin and myogenin, myoglobin is helpful in the identification of rhabdomyosarcoma and tumors with skeletal muscle differentiation. Reportedly, myoglobin is expressed on epithelial cancer cells due to changed metabolic and environmental conditions. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human full-length Myoglobin (MB) protein.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: SK-BR3 or T47D cells. Skeletal or Cardiac Muscle.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for Myoglobin

Target: Myoglobin (MB)

Alternative Name: Myoglobin

Background:

Synonyms: MB, Myoglobin, PVALB

Gene Symbol: MB

Tissue Expression: Muscle

Molecular Weight: 17 kDa

Gene ID: 4151

UniProt: P02144

Pathways: Brown Fat Cell Differentiation