S100A2 antibody (CF®640R)

Catalog No. ABIN7659685

This Mouse Monoclonal antibody specifically detects S100A2 in WB, IHC, IF, FACS and IHC (fp). It exhibits reactivity toward Human.

Quick Overview for S100A2 antibody (CF®640R) (ABIN7659685)

Target: S100A2 (S100 Calcium Binding Protein A2 (S100A2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This S100A2 antibody is conjugated to CF®640R

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: CPTC-S100A2-2

Product Details anti-S100A2 Antibody (CF®640R)

Purpose: S100A2 / S100 Calcium Binding Protein A2(CPTC-S100A2-2), CF640R conjugate

Characteristics: S100A2 belongs to the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A2 may function as a modulator against excess calcium accumulation in normal human mammary epithelial cells and also have a role in suppressing tumor cell growth. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. Cytoplasmic overexpression may also be of prognostic significance when observed in oral cancer patients, and the S100A2 has also been identified as significantly down-regulated in gastric cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human S100A2 protein

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: HeLa. A549, HACAT, BxPC3 and A431 cell lysates, Skin and squamous cell cervical carcinoma.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for S100A2

Target: S100A2 (S100 Calcium Binding Protein A2 (S100A2))

Alternative Name: S100 Calcium Binding Protein A2

Background:

Synonyms: CAN19, MGC111539, S100L

Gene Symbol: S100A2

Molecular Weight: 11.12 kDa

Gene ID: 6273

UniProt: P29034

Pathways: S100 Proteins