Recombinant SAA antibody (CF®740)

Catalog No. ABIN7659870

This anti-SAA antibody is a Rabbit Monoclonal antibody detecting SAA in IHC and IHC (fp). Suitable for Human.

Quick Overview for Recombinant SAA antibody (CF®740) (ABIN7659870)

Target: SAA (Serum Amyloid A (SAA))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SAA antibody is conjugated to CF®740

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: SAA-2868R

Product Details anti-SAA Antibody (CF®740)

Purpose: Serum Amyloid A (SAA/2868R), CF740 conjugate

Characteristics: This antibody reacts with natural and recombinant human Serum Amyloid A (SAA) and does not cross-react with other human cytokines or growth factors. Human SAA proteins are a group of apo-lipoproteins found predominantly in the high-density lipoprotein (HDL) fraction of plasma. SAA is a major acute-phase protein and precursor to amyloid A protein, which is the major constituent of the fibril deposits of reactive amyloidosis. SAA is secreted in large amounts by the liver during microbial infections or inflammatory diseases.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human serum amyloid A (SAA) protein

Isotype: IgG

Application Details

Application Notes: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody. Immunohistology (formalin): 0.25-0.5 μg/mL for 30 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA pH 9.0 for 10-20 minutes followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined by user

Comment:

Positive Control: Caki-1 cells or Pancreas or Liver

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % rBSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for SAA

Target: SAA (Serum Amyloid A (SAA))

Alternative Name: Serum Amyloid A

Background:

Synonyms: Amyloid fibril protein AA, Amyloid fibrils, PIG4, Serum amyloid A protein (SAA), Serum amyloid A1 isoform 1 (SAA1), Serum amyloid A1 isoform 2 (SAA2), Tumor protein p53 inducible protein 4 (TP53I4)

Gene Symbol: SAA

Molecular Weight: 12 kDa

Gene ID: 6288, 6289

UniProt: P02735, P0DJI8