TUBB3 antibody (AA 437-450) (CF®594)

Catalog No. ABIN7661112

This anti-TUBB3 antibody is a Mouse Monoclonal antibody detecting TUBB3 in WB, IHC and IHC (fp). Suitable for Human.

Quick Overview for TUBB3 antibody (AA 437-450) (CF®594) (ABIN7661112)

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TUBB3 antibody is conjugated to CF®594

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: TUBB3-3731

Product Details anti-TUBB3 Antibody (CF®594)

Binding Specificity: AA 437-450

Purpose: Tubulin beta 3 / TUBB3 (Neuronal & Stem Cell Marker)(TUBB3/3731), CF594 conjugate

Characteristics: This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: A synthetic peptide (aa 437-450) of human Tubulin beta 3 protein (TUBB3), coupled to KLH.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: U87, A375, Raji, HEP2 cells. Brain and Testis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Alternative Name: TUBB3

Background:

Synonyms: beta 3 tubulin, CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, M(beta)3, M(beta)6, MC1R, Neuron specific beta III Tubulin, Neuron-specific class III beta-tubulin, TUBB3, TUBB4, Tubulin beta-3, Tubulin beta-4, Tubulin beta-III

Gene Symbol: TUBB3

Molecular Weight: 55 kDa

Gene ID: 10381

UniProt: Q13509

Pathways: Microtubule Dynamics, M Phase