Tumor Protein p73 antibody (Biotin)

Catalog No. ABIN7661427

This anti-Tumor Protein p73 antibody is a Mouse Monoclonal antibody detecting Tumor Protein p73 in IHC and IHC (fp). Suitable for Human.

Quick Overview for Tumor Protein p73 antibody (Biotin) (ABIN7661427)

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tumor Protein p73 antibody is conjugated to Biotin

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: P73-2531

Product Details anti-Tumor Protein p73 Antibody (Biotin)

Purpose: p73 (Tumor Suppressor)(P73/2531), Biotin conjugate

Characteristics: p73 shares considerable sequence similarity with the widely-studied tumor suppressor gene p53. The p73 gene maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, unlike p53, p73 does not appear to be activated by DNA damaging agents. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human TP73 protein

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: HeLa, Jurkat, HEK293 cell lysates. Human kidney or bladder carcinoma.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for Tumor Protein p73

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Alternative Name: p73

Background:

Synonyms: p53-like transcription factor, p53-related protein, p73, TP73, Tumor protein p73

Gene Symbol: TP73

Molecular Weight: 73 kDa

Gene ID: 7161

UniProt: O15350

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus