YBX1 antibody (CF®405S)

Catalog No. ABIN7662063

This anti-YBX1 antibody is a Mouse Monoclonal antibody detecting YBX1 in IHC and IHC (fp). Suitable for Human.

Quick Overview for YBX1 antibody (CF®405S) (ABIN7662063)

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This YBX1 antibody is conjugated to CF®405S

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: YBX1-2430

Product Details anti-YBX1 Antibody (CF®405S)

Purpose: YBX1 / Y-box Binding Protein 1 / YB-1 (Tumor Biomarker)(YBX1/2430), CF405S conjugate

Characteristics: The specificity of this monoclonal antibody to its intended target was validated by HuProt™, Array, containing more than 19,000 full-length human proteins. Y-box binding protein-1 (YBX1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus, YBX1 protein orchestrates transcription of proliferation-related genes, whereas in the cytoplasm it associates with mRNA and directs translation. In human tumor entities, such as breast, lung and prostate cancer, cellular YBX1 expression indicates poor clinical outcome, suggesting that YBX1 is an attractive marker to predict patients' prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human full-length YBX1 protein

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Positive Control: MCF-7, HEK293 or PC12 cells. Prostate, Breast or Lung Carcinoma.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % BSA, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Storage: 4 °C

Storage Comment:

Stable at room temperature or 37°C for 7 days.

Protect from light

Store at 2 to 8°C. Protect fluorescent conjugates from light

Expiry Date: 24 months

Target Details for YBX1

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Alternative Name: Y-box Binding Protein 1

Background:

Synonyms: BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1

Gene Symbol: YBX1

Molecular Weight: 36 kDa

Gene ID: 4904

UniProt: P67809

Pathways: Regulation of Muscle Cell Differentiation