CD163 antibody

Catalog No. ABIN7669987

The Mouse Monoclonal anti-CD163 antibody has been validated for FACS. It is suitable to detect CD163 in samples from Human.

Quick Overview for CD163 antibody (ABIN7669987)

Target: CD163

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD163 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: MAC2-158

Product Details anti-CD163 Antibody

Purpose: Purified Anti-Human CD163 Antibody[MAC2-158]

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD163

Target: CD163

Alternative Name: CD163

Background: GHI/,SCARI,CD163,M130,MM130,SCARI1,ED2(rat),GHI/61,Hemoglobin/Haptoglobin Complex Receptor,macrophage-associated antigen,p155,RM3/1, GHI/61,The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

UniProt: Q86VB7