CD38 antibody
Quick Overview for CD38 antibody (ABIN7670012)
Target
See all CD38 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Purified Anti-Human CD38 Antibody[AT13/5]
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Isotype
- IgG1, kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- ≥ 1 mg/mL
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Buffer
- Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- avoid freeze / thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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Expiry Date
- 12 months
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- CD38
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Background
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1,CD38,2'-phospho-ADP-ribosyl cyclase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,ADPRC 1,Cyclic ADP-ribose hydrolase 1,cADPr hydrolase 1,T10,CD38,CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose . CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells . Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.
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UniProt
- P28907
Target
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