CD52 antibody

Catalog No. ABIN7670028

This Rabbit Monoclonal antibody specifically detects CD52 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD52 antibody (ABIN7670028)

Target: CD52

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD52 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: Campath-1G

Product Details anti-CD52 Antibody

Purpose: Purified Anti-Human CD52 Antibody[Campath-1G]

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CD52

Target: CD52

Alternative Name: CD52

Background: CDW,Epididymal secretory protein E,Human epididymis-specific protein,CAMPATH,CAMPATH-1,CAMPATH-1 antigen,CD52 antigen,CD52 Molecule,Epididymal secretory protein E5,HEL-S-171mP,Human epididymis-specific protein 5,CDW52,HE5,CD52, HE5,CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a large N-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductive tract and on virtually all lymphocytes (T and B cells), as well as macrophages/monocytes, eosinophils, and red cells. CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target for complement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target for chronic lymphocytic leukemia (CLL)/lymphoma and immunosuppression.

UniProt: P31358