CD7 antibody
Quick Overview for CD7 antibody (ABIN7670030)
Target
See all CD7 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Purpose
- Purified Anti-Human CD7 Antibody[3A1e]
-
Isotype
- IgG2b, kappa
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- ≥ 1 mg/mL
-
Buffer
- Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.
-
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- avoid freeze / thaw cycles.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
-
Expiry Date
- 12 months
-
-
- CD7
-
Alternative Name
- CD7
-
Background
- T-cell antigen CD7,CD7,GP40,T-cell leukemia antigen,T-cell surface antigen Leu-9,TP41,TP41,CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.
-
UniProt
- P09564
-
Pathways
- Cell-Cell Junction Organization
Target
-