CXCR4 antibody

Catalog No. ABIN7670044

The Mouse Monoclonal anti-CXCR4 antibody has been validated for FACS. It is suitable to detect CXCR4 in samples from Human.

Quick Overview for CXCR4 antibody (ABIN7670044)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CXCR4 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: 12G5

Product Details anti-CXCR4 Antibody

Purpose: Purified Anti-Human CD184 Antibody[12G5]

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Alternative Name: CD184

Background: LCR,CXCR,C-X-C chemokine receptor type,LAP,CD184,D2S201E,FB22,HM89,HSY3RR,LAP-3,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM,WHIMS,CXCR4,C-X-C chemokine receptor type 4,Fusin,SDF 1 receptor, Fusin, LESTR,CD184 antigen,Chemokine (C X C motif) receptor 4,Chemokine CXC Motif Receptor 4,C-X-C motif chemokine receptor 4,CXCR-4,CXC-R4,LAP 3,Leukocyte derived seven transmembrane domain receptor,Leukocyte-derived seven transmembrane domain receptor,Lipopolysaccharide associated protein 3,Neuropeptide Y receptor Y3,NPYY3,Probable G protein coupled receptor lcr1 homolog,SDF-1 receptor,SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR,Stromal cell derived factor 1 receptor,Stromal cell-derived factor 1 receptor,This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events