Galectin 3 antibody

Catalog No. ABIN7670062

The Rat Monoclonal anti-Galectin 3 antibody has been validated for FACS. It is suitable to detect Galectin 3 in samples from Human and Mouse.

Quick Overview for Galectin 3 antibody (ABIN7670062)

Target: Galectin 3 (LGALS3)

Reactivity: Human, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Galectin 3 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: M3-38

Product Details anti-Galectin 3 Antibody

Purpose: Purified Anti-Mouse/Human GAL3 Antibody[M3/38]

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Galectin 3

Target: Galectin 3 (LGALS3)

Alternative Name: GAL3

Background: MAC,Galactose-specific lectin,Galactoside-Binding Soluble,Galectin,Lectin L,GAL,CBP,LGALS3,CBP35,GAL3,GALBP,GALIG,L31,LGALS2,MAC2,Galactoside-Binding Soluble 3,Lectin,Galectin-3,Gal-3,L-31,35 kDa lectin,CBP 35,Galactose-specific lectin 3,IgE-binding protein,Laminin-binding protein,Lectin L-29,Mac-2 antigen,Carbohydrate binding protein 35,Carbohydrate-binding protein 35,galactose binding,galactoside binding soluble 3,Galactoside-binding protein,galectin 3,Galectin 3 internal gene,Galectin3,GBP,IgE binding protein,included,L 31,L 34,L-34 galactoside-binding lectin,Lectin,Galactoside-Binding Soluble 3,LEG3,MAC 2 antigen,Mac-2,Macrophage galactose-specific lectin,MGC105387,P35,soluble 3,Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.

UniProt: P17931

Pathways: RTK Signaling