SLAMF1 antibody

Catalog No. ABIN7670121

This Rat Monoclonal antibody specifically detects SLAMF1 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for SLAMF1 antibody (ABIN7670121)

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This SLAMF1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: TC15-12F12-2

Product Details anti-SLAMF1 Antibody

Purpose: Purified Anti-Mouse CD150 Antibody[TC15-12F12.2]

Isotype: IgG2a, lambda

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze / thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for SLAMF1

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Alternative Name: CD150

Background: SLAM family member,SLAMF,CD 150,CD150,CD150 antigen,Signaling lymphocytic activation molecule,SLAM family member 1,Slam,Slamf1, IPO-3,CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.

UniProt: Q9QUM4