TCR gamma/delta antibody

Catalog No. ABIN7670199

This Mouse Monoclonal antibody specifically detects TCR gamma/delta in FACS. It exhibits reactivity toward Human.

Quick Overview for TCR gamma/delta antibody (ABIN7670199)

Target: TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TCR gamma/delta antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: B1

Product Details anti-TCR gamma/delta Antibody

Purpose: AF/LE Purified Anti-Human TCRγ/δ Antibody[B1]

Endotoxin Level: Low Endotoxin

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: ≥ 1 mg/mL

Buffer: Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method.

Preservative: Azide free

Handling Advice: avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Expiry Date: 12 months

Target Details for TCR gamma/delta

Target: TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))

Alternative Name: TCRgamma/delta

Background: TRDC,T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ is involved in the recognition of certain bacterial, self-CD1 Molecule, and tumor antigens bound to MHC class I. The γ/δ TCR associates with CD3 and is expressed on a subset of T cells found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8-, some are CD8+. T cells expressing the γ/δ TCR have been shown to play a role in oral tolerance, innate immune response for some tumor cells, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation.

UniProt: B7Z8K6