ITGAL antibody (PE)

Catalog No. ABIN7670226

This Mouse Monoclonal antibody specifically detects ITGAL in FACS. It exhibits reactivity toward Human.

Quick Overview for ITGAL antibody (PE) (ABIN7670226)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGAL antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 38

Product Details anti-ITGAL Antibody (PE)

Purpose: PE Anti-Human CD11a Antibody[38]

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 5 μL/tests

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Handling Advice: Please protected from prolonged exposure to light and do not freeze.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months.

Expiry Date: 12 months

Target Details for ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Alternative Name: CD11a

Background: Muc-18,MCAM,Mel-CAM,S-endo,CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

UniProt: P43121

Pathways: Activated T Cell Proliferation, Integrin Complex