Cathepsin L antibody

Catalog No. ABIN7670502

The Rabbit Polyclonal anti-Cathepsin L antibody has been validated for IHC. It is suitable to detect Cathepsin L in samples from Human.

Quick Overview for Cathepsin L antibody (ABIN7670502)

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin L antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Cathepsin L Antibody

Purpose: Cathepsin L Polyclonal Antibody

Purification: Antigen Affinity Purification

Immunogen: Recombinant Human Cathepsin L protein expressed by Mammalian

Isotype: IgG

Application Details

Application Notes: IHC 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % proclin 300, 1 % protective protein and 50 % glycerol, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Cathepsin L

Target: Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

Alternative Name: Cathepsin L

Background: CATL,CATL1,CTSL,CTSL1,Cathepsin L1,Cathepsin L1 light chain,CathepsinL,FLJ31037,MEP,MGC123162,Major excreted protein,cathepsin L,cb15,ctsl1b,hgg1,The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.

UniProt: P07711

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades