Ubiquitin antibody

Catalog No. ABIN7670506

This anti-Ubiquitin antibody is a Rabbit Polyclonal antibody detecting Ubiquitin in IHC and IF. Suitable for Human and Rat.

Quick Overview for Ubiquitin antibody (ABIN7670506)

Target: Ubiquitin (Ub)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ubiquitin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Ubiquitin Antibody

Purpose: Ubiquitin Polyclonal Antibody

Purification: Antigen Affinity Purification

Immunogen: Recombinant Human Ubiquitin protein expressed by E.coli

Isotype: IgG

Application Details

Application Notes: IF 1:100-1:200,IHC 1:200-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.05 % proclin 300, 1 % protective protein and 50 % glycerol, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Ubiquitin

Target: Ubiquitin (Ub)

Alternative Name: Ubiquitin

Background: HEL-S-50,ubiquitin B,HEL-S,UBB,HEL-S-50,ubiquitin B,Polyubiquitin-B,Ubiquitin,This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.

UniProt: P0CG47

Pathways: Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway