Fetuin A antibody

Catalog No. ABIN7670525

This Rabbit Polyclonal antibody specifically detects Fetuin A in ELISA. It exhibits reactivity toward Human.

Quick Overview for Fetuin A antibody (ABIN7670525)

Target: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fetuin A antibody is un-conjugated

Application: ELISA

Product Details anti-Fetuin A Antibody

Purpose: Fetuin A/AHSG Polyclonal Antibody(Capture/Detector)

Purification: Antigen Affinity Purification

Immunogen: Recombinant Human Fetuin A/AHSG protein expressed by Mammalian

Isotype: IgG

Application Details

Application Notes: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for Fetuin A

Target: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Alternative Name: Fetuin A/AHSG

Background: Alpha-2-HS-glycoprotein,Alpha-2-Z-globulin,Ba-alpha-2-glycoprotein,Fetuin-A,AHSG,FETUA,Fetuin-A,also named as Alpha2-HS glycoprotein (AHSG),is a member of cystatin superfamily of protease inhibitors. It is a highly expressed glycoprotein in various fetal tissues whereas it is mainly expressed by the liver in adults. Fetuin A,an extracellular inhibitor of transforming growth factor β,is a profibrogenic stimulus in liver disease. Circulating fetuin-A may be a beneficial serum biomarker in the detection of liver and vascular fibrosis progression in patients with non-alcoholic fatty liver disease. It is also involved in several functions,such as endocytosis,brain development and the formation of bone tissue. Fetuin-A exerts its effects on the cardiovascular system by two different mechanisms. On the one hand it inhibits ins signaling and induces ins resistance contributing to the onset of atherosclerosis and on the other hand it inhibits calcium deposition and protects from vascular calcification.

UniProt: P02765