Cathepsin B antibody

Catalog No. ABIN7670553

The Rabbit Polyclonal anti-Cathepsin B antibody has been validated for ELISA. It is suitable to detect Cathepsin B in samples from Human.

Quick Overview for Cathepsin B antibody (ABIN7670553)

Target: Cathepsin B (CTSB)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin B antibody is un-conjugated

Application: ELISA

Product Details anti-Cathepsin B Antibody

Purpose: Cathepsin B Polyclonal Antibody(Capture/Detector)

Purification: Antigen Affinity Purification

Immunogen: Recombinant Human Cathepsin B protein expressed by Mammalian

Isotype: IgG

Application Details

Application Notes: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for Cathepsin B

Target: Cathepsin B (CTSB)

Alternative Name: Cathepsin B

Background: APPS,CPSB,CTSB(Cathepsin B) is also named as CPSB and belongs to the peptidase C1 family. It participates in intracellular degradation and turnover of proteins. Cathepsin B precursors found in human malignant ascites fluid do not possess mannose-rich carbohydrates suggesting that a defect in the post translational processing of carbohydrate moieties on tumor. Cathepsin B exists as both glycosylated and unglycosylated forms. In rat macrophages and hepatocytes pro- cathepsin B is 39 kDa (unglycosylated =35 kDa),whereas in human fibroblasts procathepsin B is 44.5-46 kDa (unglycosylated=39 kDa). It can be detected the 43 kDa form of pro-CTSB,31 kDa and 25 kDa mature forms in mouse brain by western blot.

UniProt: P07858

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades