CCL21 antibody

Catalog No. ABIN7670566

This anti-CCL21 antibody is a Rabbit Polyclonal antibody detecting CCL21 in ELISA. Suitable for Mouse.

Quick Overview for CCL21 antibody (ABIN7670566)

Target: CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL21 antibody is un-conjugated

Application: ELISA

Product Details anti-CCL21 Antibody

Purpose: CCL21/6Ckine Polyclonal Antibody(Capture/Detector)

Purification: Antigen Affinity Purification

Immunogen: Recombinant Mouse CCL21/6Ckine protein expressed by E.coli

Isotype: IgG

Application Details

Application Notes: ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for CCL21

Target: CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))

Alternative Name: CCL21/6Ckine

Background: TCA,Scya,Beta-Chemokine Exodus,Thymus-Derived Chemotactic Agent,6Ckine,Beta-Chemokine Exodus-2,C-C Motif Chemokine 21a,Small-Inducible Cytokine A21a,TCA4,Thymus-Derived Chemotactic Agent 4,Scya21,Scya21a,Ccl21a,C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine beta (CCchemokine) family. Mouse CCL21 cDNA encodes a 133 amino acid residue protein with a 23 residue signalpeptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms whileCCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 andCXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro forthymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 showspreferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes tosecondary lymphoid organs.

UniProt: P84444

Pathways: Regulation of Actin Filament Polymerization