Galectin 3 antibody

Catalog No. ABIN7670615

This Rabbit Polyclonal antibody specifically detects Galectin 3 in IHC, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for Galectin 3 antibody (ABIN7670615)

Target: Galectin 3 (LGALS3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Galectin 3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Galectin 3 Antibody

Purpose: Galectin-3 Polyclonal Antibody

Purification: Antigen Affinity Purification

Immunogen: Recombinant Human Galectin-3 protein expressed by E.coli

Isotype: IgG

Application Details

Application Notes: IHC 1:650-1:1250,IF 1:50-1:200,ELISA Capture 2-8 μg/mL,ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for Galectin 3

Target: Galectin 3 (LGALS3)

Alternative Name: Galectin-3

Background: GAL3,GaL-3,GaLectin-3,35 kDa Lectin,Carbohydrate-binding protein 35 (CBP 35),GaLactose-specific Lectin 3,GaLactoside-binding protein (GALBP),IgE-binding protein,LGALS3,MAC2,Galactose-specific lectin which binds IgE. May mediate with the alpha-3,beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1,required for terminal differentiation of columnar epithelial cells during early embryogenesis.In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion,chemoattraction of monocytes macrophages,opsonization of apoptotic neutrophils,and activation of mast cells. Together with TRIM16,coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16l1 and BECN1 in response to damaged endomembranes.

UniProt: P17931

Pathways: RTK Signaling