Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C Valid for 1 month or -20°C Valid for 12 months
Expiry Date
12 months
Target
GSTA1
(Glutathione S-Transferase alpha 1 (GSTA1))
Alternative Name
gsta1
Background
GSTA1,GST2,GSTA1-1,GTH1,GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs,GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adenocarcinoma (Caco-2) cells in culture undergo spontaneous differentiation into mature enterocytes in association with progressive increases in expression of glutathione S-transferase alpha-1 (GSTA1). GSTA1 levels may play a role in modulating enterocyte proliferation but do not influence differentiation or apoptosis. GSTA1 may play a key role during pregnancy.