IL32 antibody

Catalog No. ABIN7670668

This anti-IL32 antibody is a Rat Monoclonal antibody detecting IL32 in ELISA (Detection). Suitable for Human.

Quick Overview for IL32 antibody (ABIN7670668)

Target: IL32 (Interleukin 32 (IL32))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This IL32 antibody is un-conjugated

Application: ELISA (Detection)

Clone: 4D9

Product Details anti-IL32 Antibody

Purpose: IL-32 Monoclonal Antibody(Detector)

Purification: Protein A/G Purification

Immunogen: Recombinant Human IL-32 protein expressed by E.coli

Isotype: IgG1

Application Details

Application Notes: ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for IL32

Target: IL32 (Interleukin 32 (IL32))

Alternative Name: IL-32

Background: Interleukin-32,IL-32,Natural killer cells protein 4,Tumor necrosis factor alpha-inducing factor,IL32,NK4,TAIF,IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active, although all isoforms are biologically active. IL-32, a cytokine produced mainly by T, natural killer, and epithelial cells induces significant amounts of TNFalpha and MIP-2 and increases the production of both cytokines in a dose-dependent manner. IL-32 has been implicated in inflammatory disorders, Mycobacterium tuberculosis infections, inflammatory bowel disease, and influenza A virus infection, as well as in some autoimmune diseases, such as rheumatoid arthritis, ulcerative colitis, and in the human stomach cancer, human lung cancer, and breast cancer tissues. Thus, IL-32 expression might be valuable as a biomarker for cancer.

UniProt: P24001