IL-8 antibody

Catalog No. ABIN7670673

The Rat Monoclonal anti-IL-8 antibody has been validated for ELISA (Capture). It is suitable to detect IL-8 in samples from Human.

Quick Overview for IL-8 antibody (ABIN7670673)

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-8 antibody is un-conjugated

Application: ELISA (Capture)

Clone: 5G4

Product Details anti-IL-8 Antibody

Purpose: IL-8/CXCL8 Monoclonal Antibody(Capture)

Purification: Protein A/G Purification

Immunogen: Recombinant Human IL-8/CXCL8 protein expressed by Mammalian

Isotype: IgG1

Application Details

Application Notes: ELISA Capture 2-8 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for IL-8

Target: IL-8 (IL8) (Interleukin 8 (IL8))

Alternative Name: IL-8/CXCL8

Background: IL8,CXCL8,GCP-1,GCP1,LECT,LUCT,LYNAP,MDNCF,MONAP,NAF,NAP-1,NAP1,3-10C,AMCF-I,K60,Interleukin 8 (IL-8),also known as CXCL8,which is a member of the CXC chemokine family. This chemokine is secreted by a variety of cell types including monocyte/macrophages,T cells,neutrophils,fibroblasts,endothelial cells,and various tumor cell lines in response to inflammatory stimuli. IL-8 has two primary functions. It induces chemotaxis in target cells,primarily neutrophils but also other granulocytes,causing them to migrate toward the site of infection. IL-8 also induces phagocytosis once they have arrived. This gene is believed to play a role in the pathogenesis of bronchiolitis,a common respiratory tract disease caused by viral infection. IL-8 is also known to be a potent promoter of angiogenesis. IL-8 has been associated with tumor angiogenesis,metastasis,and poor prognosis in breast cancer. IL-8 may present a novel therapeutic target for estrogen driven breast carcinogenesis and tumor progression.

UniProt: P10145

Pathways: TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy