PLAUR antibody

Catalog No. ABIN7670723

This Rat Monoclonal antibody specifically detects PLAUR in ELISA (Detection). It exhibits reactivity toward Human.

Quick Overview for PLAUR antibody (ABIN7670723)

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This PLAUR antibody is un-conjugated

Application: ELISA (Detection)

Clone: 6B5

Product Details anti-PLAUR Antibody

Purpose: uPAR Monoclonal Antibody(Detector)

Purification: Protein A/G Purification

Immunogen: Recombinant Human uPAR protein expressed by Mammalian

Isotype: IgG1

Application Details

Application Notes: ELISA Detector 0.1-0.4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Sterile PBS , pH 7.4

Preservative: Without preservative

Handling Advice: Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C Valid for 1 month or -20°C Valid for 12 months

Expiry Date: 12 months

Target Details for PLAUR

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Alternative Name: uPAR

Background: CD87,U-PAR,URKR,This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.

UniProt: Q03405

Pathways: Inositol Metabolic Process