SIGLEC9 antibody (APC)

Catalog No. ABIN7672709

This Mouse Monoclonal antibody specifically detects SIGLEC9 in FACS. It exhibits reactivity toward Human.

Quick Overview for SIGLEC9 antibody (APC) (ABIN7672709)

Target: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIGLEC9 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: K8

Product Details anti-SIGLEC9 Antibody (APC)

Purpose: APC Anti-Human CD329 Antibody

Purification: 0

Purity: 0

Isotype: IgG1, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for SIGLEC9

Target: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Alternative Name: CD329

Background:

Synonyms: Siglec-9|Sialic acid-binding Ig-like lectin-9,

Background: Siglecs are cell surface receptors belonging to the immunoglobulin superfamily that recognize sugar antigens. The extracellular domain of siglec-9 contains an IgV region, which binds sialic acid, followed by two IgC regions. Siglec 9 and siglec 6-8,10-12 are CD33 (siglec 3) like siglecs, which have two ITIMs in the cytoplasmic tails, suggesting their functional involvement in signal transduction. It is highly expressed on neutrophils and monocytes, and at lower levels on the subpopulations of T and B lymphocytes and NK cells. Siglec-9 plays a role in negative regulation of T cell activation, and it also affects neutrophil apoptosis.

Molecular Weight: 0

Gene ID: 27180

UniProt: Q9Y336