CD70 antibody (APC)

Catalog No. ABIN7672754

This Mouse Monoclonal antibody specifically detects CD70 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD70 antibody (APC) (ABIN7672754)

Target: CD70 (CD70 Molecule (CD70))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD70 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: 113-16

Product Details anti-CD70 Antibody (APC)

Purpose: APC Anti-Human CD70 Antibody

Purification: 0

Purity: 0

Isotype: IgG1, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for CD70

Target: CD70 (CD70 Molecule (CD70))

Alternative Name: CD70

Background:

Synonyms: CD27 ligand|CD27L|Ki-24 antigen|Tumor necrosis factor ligand superfamily|member 7 (TNFSF7)

Background: CD70, also known as CD27L, is a 50 kD type II transmembrane glycoprotein and member of the tumor necrosis factor superfamily. CD70 is expressed on activated T, B and NK cells, activated plasmacytoid dendritic cells (pDCs), and chronic B cell lymphocytic leukemia and large B cell lymphomas. CD70 costimulates T cell proliferation and differentiation. It plays a role in the pDC-induced B cell differentiation. The ligand of CD70 is CD27.

Molecular Weight: 0

Gene ID: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints