IFNGR1 antibody (APC)

Catalog No. ABIN7672792

This anti-IFNGR1 antibody is a Rat Monoclonal antibody detecting IFNGR1 in FACS. Suitable for Mouse.

Quick Overview for IFNGR1 antibody (APC) (ABIN7672792)

Target: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IFNGR1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: GR-20

Product Details anti-IFNGR1 Antibody (APC)

Purpose: APC Anti-Mouse CD119 Antibody

Purification: 0

Purity: 0

Isotype: IgG2a, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for IFNGR1

Target: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Alternative Name: CD119

Background:

Synonyms: CD119|IFN-gamma-R-alpha|IFN-gamma-R1|Ifngr1|Interferon gamma receptor 1

Background: CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

Molecular Weight: 0

Gene ID: 15979

UniProt: P15261

Pathways: Interferon-gamma Pathway