Complement C4 antibody (Chain alpha)

Catalog No. ABIN7672925

This Rabbit Polyclonal antibody specifically detects Complement C4 in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Complement C4 antibody (Chain alpha) (ABIN7672925)

Target: Complement C4 (C4) (Complement 4 (C4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Complement C4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-Complement C4 Antibody

Binding Specificity: Chain alpha

Purpose: C4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1028-1336

Immunogen: complement component 4A(Rodgers blood group)

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:6000, IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for Complement C4

Target: Complement C4 (C4) (Complement 4 (C4))

Alternative Name: C4

Background:

Synonyms: Complement C4-A|Acidic complement C4|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2|Complement C4 beta chain|Complement C4-A alpha chain|C4a anaphylatoxin|C4b-A|C4d-A|Complement C4 gamma chain|C4A|CO4|CPAMD2

Background: Complement C4, a component of the classical complement pathway, has an important role in innate immune function. C4 protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains (molecular wights 95, 78, and 31 kDa) prior to secretion. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. This antibody can recognize C4 precursor, C4 alpha chain, C4b, and C4d.

Molecular Weight: 95 kDa

Gene ID: 720

UniProt: P0C0L4

Pathways: Complement System