Claudin 4 antibody

Catalog No. ABIN7672979

This Rabbit Polyclonal antibody specifically detects Claudin 4 in WB, ELISA, IHC and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Claudin 4 antibody (ABIN7672979)

Target: Claudin 4 (CLDN4)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-Claudin 4 Antibody

Purpose: CLDN4-specific antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: claudin 4

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for Claudin 4

Target: Claudin 4 (CLDN4)

Alternative Name: CLDN4

Background:

Synonyms: Claudin-4|Clostridium perfringens enterotoxin receptor (CPE-R, CPE-receptor)|Williams-Beuren syndrome chromosomal region 8 protein|CLDN4|CPER|CPETR1|WBSCR8

Background: Claudins are a family of proteins that are the most important components of the tight junctions, where they establish the paracellular barrier that controls the flow of molecules in the intercellular space between the cells of an epithelium. 23 claudins have been identified. They are small(20-27 kDa) proteins with very similar structure. They have four transmembrane domains, with the N-terminus and the C-terminus in the cytoplasm. This antibody is specifically against claudin 4.

Molecular Weight: 22 kDa

UniProt: O14493

Pathways: Hepatitis C