CD6 antibody (FITC)

Catalog No. ABIN7673244

The Rat Monoclonal anti-CD6 antibody has been validated for FACS. It is suitable to detect CD6 in samples from Mouse.

Quick Overview for CD6 antibody (FITC) (ABIN7673244)

Target: CD6

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD6 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: OX-129

Product Details anti-CD6 Antibody (FITC)

Purpose: FITC Anti-Mouse CD6 Antibody

Purification: 0

Purity: 0

Isotype: IgG2a, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for CD6

Target: CD6

Alternative Name: CD6

Background:

Synonyms: CD6/TP120

Background: CD6, a 100 kD monomeric T cell surface glycoprotein, is a member of the scavenger receptor cysteine-rich protein superfamily. It is expressed on mouse thymocytes and splenic T cells and neurons, but not on splenic B cells. CD6 has a long cytoplasmic tail in mice, with two proline-rich domains that interact with the -SH3 domain binding sequence. CD6 binding to its ligand, CD166 (ALCAM), serves as a costimulatory molecule through its interaction with SLP-76. CD6 mediated signaling may contribute to thymocyte survival and functional avidity in mice and men.

Molecular Weight: 0

Gene ID: 12511

UniProt: Q61003