HBSAg antibody

Catalog No. ABIN7673361

The Mouse Monoclonal anti-HBSAg antibody has been validated for ELISA. It is suitable to detect HBSAg in samples from Human.

Quick Overview for HBSAg antibody (ABIN7673361)

Target: HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HBSAg antibody is un-conjugated

Application: ELISA

Clone: 4A10

Product Details anti-HBSAg Antibody

Purpose: HBsAg antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: HBsAg

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 20 mM PBS, 0.1 % proclin300,

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: store at 2-8°C up to 21 days, -20°C for long-term storage. Don't repeated freeze-thaw.

Expiry Date: 3 weeks

Target Details for HBSAg

Target: HBSAg (HBsAg) (Hepatitis B Virus Surface Antigen (HBsAg))

Alternative Name: HBsAg

Target Type: Viral Protein

Background:

Synonyms: Large envelope protein|Large surface protein|Large S protein|Major surface antigen

Background: The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assumes fusion between virion membrane and endosomal membrane(Probable). In its internal conformation the protein plays a role in virion morphogenesis and mediates the contact with the nucleocapsid like a matrix protein.

Molecular Weight: 43 kDa