HNRNPA1 antibody

Catalog No. ABIN7673376

The Rabbit Polyclonal anti-HNRNPA1 antibody has been validated for WB, ELISA, IHC and IF. It is suitable to detect HNRNPA1 in samples from Human, Mouse and Rat.

Quick Overview for HNRNPA1 antibody (ABIN7673376)

Target: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-HNRNPA1 Antibody

Purpose: HNRNPA1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: heterogeneous nuclear ribonucleoprotein A1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for HNRNPA1

Target: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Alternative Name: HNRNPA1

Background:

Synonyms: Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1)|Helix-destabilizing protein|Single-strand RNA-binding protein|hnRNP core protein A1|Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed|HNRNPA1|HNRPA1

Background: This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome.

Molecular Weight: 34 kDa, 38 kDa

Gene ID: 3178

UniProt: P09651